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Glutarate regulates T cell metabolism and anti-tumour immunity.
Minogue E, Cunha PP, Wadsworth BJ, Grice GL, Sah-Teli SK, Hughes R, Bargiela D, Quaranta A, Zurita J, Antrobus R, Velica P, Barbieri L, Wheelock CE, Koivunen P, Nathan JA, Foskolou IP, Johnson RS. Minogue E, et al. Among authors: sah teli sk. Nat Metab. 2023 Oct;5(10):1747-1764. doi: 10.1038/s42255-023-00855-2. Epub 2023 Aug 21. Nat Metab. 2023. PMID: 37605057 Free PMC article.
Iron drives anabolic metabolism through active histone demethylation and mTORC1.
Shapiro JS, Chang HC, Tatekoshi Y, Zhao Z, Waxali ZS, Hong BJ, Chen H, Geier JA, Bartom ET, De Jesus A, Nejad FK, Mahmoodzadeh A, Sato T, Ramos-Alonso L, Romero AM, Martinez-Pastor MT, Jiang SC, Sah-Teli SK, Li L, Bentrem D, Lopaschuk G, Ben-Sahra I, O'Halloran TV, Shilatifard A, Puig S, Bergelson J, Koivunen P, Ardehali H. Shapiro JS, et al. Among authors: sah teli sk. Nat Cell Biol. 2023 Oct;25(10):1478-1494. doi: 10.1038/s41556-023-01225-6. Epub 2023 Sep 25. Nat Cell Biol. 2023. PMID: 37749225
A histone methylation-MAPK signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreatic cancer.
Brown BA, Myers PJ, Adair SJ, Pitarresi JR, Sah-Teli SK, Campbell LA, Hart WS, Barbeau MC, Leong K, Seyler N, Kane W, Lee KE, Stelow E, Jones M, Simon MC, Koivunen P, Bauer TW, Stanger BZ, Lazzara MJ. Brown BA, et al. Among authors: sah teli sk. Cancer Res. 2024 Mar 12. doi: 10.1158/0008-5472.CAN-22-2945. Online ahead of print. Cancer Res. 2024. PMID: 38471099